Shapira Lior

Professor and Chair Department of Periodontology
Hebrew University - Hadassah
Faculty of Dental Medicine
P. O. Box 12272
Jerusalem, Israel

E-mail: shapiral@cc.huji.ac.il
Tel: +972-2-677-6126
Fax: +972-2-643-8705


Born 1956, Tel Aviv;
D.M.D. 1986;
Ph.D. 1995, Hebrew Univ.;
Lect. 1993;
Sen. Lect. 1996;
Assoc. Prof. 1999;
Prof. 2004.

Research Interests:

  • The relationships between periodontal infection and systemic diseases in animal models;
  • Osteoblast responses to titanium surfaces (implantology)
  • Clinical periodontology and implantology.
  • Cytokine responses to periodontal pathogens;
Effect of periodontal pathogens on T-cell functions.

Recent publications:

 

Houri-Haddad Y, Karaka L, Stabholz A, Soskolne A, Shapira L . 2004 . Tetracycline Conditioning augmented the in vivo Inflammatory Response Induced by Cementum Extracts . Journal of Periodontology , 75:388-392 .

Bimstein E, Sapir S, , Houri-Haddad Y, Dibart S, Van Dyke TE, Shapira L . 2004 . The relationships between P. gingivalis infection and local and systemic factors in children . Journal of Periodontology , 75(10):1371-6.

J, Shai E, Zaks B,, Halabi H, Houri-Haddad Y, Shapira L , Palmon A. 2004 . Immunosuppresion induced by Porphyromonas gingivalis infection increases murine morbidity and mortality due to Cytomegalovirus infection. Infection and Immunity , 72(10): 5791-5798.

Kohavi D, Azran G, Shapira L , Casap N. 2004 . Retrospective clinical review of dental implants placed in a university training program. Journal of Oral Implantology , 30(1):23-9.

Wilensky A, Gabet Y, Yumoto H, Houri-Haddad Y, Shapira L . . 2005. Three-Dimensional Quantification of Alveolar Bone Loss in Porphyromonas gingivalis-Infected Mice Using Micro-Computed Tomography.
Journal of Periodontology , 76(8):1282-6.

Houri-Haddad Y, Soskolne WA, Halabi A , Shapira L . 2005 . The effect of immunization on the response to P. gingivalis infection in mice is adjuvant-dependent. Journal of Clinical Periodontology , 32:933-7.

Mizrahi B, Shapira L , Domb AJ, Houri-Haddad Y. 2006. Citrus oil and MgCl2 as antibacterial and anti-inflammatory agents . Journal of Periodonology 77(6):963-8.

Ezernitchi AV, Vaknin I, Cohen-Daniel L, Levy O, Manaster E, Halabi A, Pikarsky E, Shapira L , Baniyash M. 2006. TCR zeta down-regulation under chronic inflammation is mediated by myeloid suppressor cells differentially distributed between various lymphatic organs. Journal of Immunology 177(7):4763-72.

Burns E, Bacharach G, Shapira L , Nussaum G . In Press . TLR2 is required for the innate response to Porphyromonas gingivalis : activation leads to bacterial persistence and TLR2 deficiency attenuates induced alveolar bone resorption Journal of Immunology ("Cutting Edge").